Are SITAXPERT TRIO 10/100/500 and JANUPTIN TRIO PLUS the same?

Name: SITAXPERT TRIO 10/100/500
Brand: Medingen
SKU: 48070
Price: 100.00 INR
Availability: InStock

Yes, SITAXPERT TRIO 10/100/500 and JANUPTIN TRIO PLUS contain the same active salt (DAPAGLIFLOZIN 10MG + SITAGLIPTIN 100MG + METFORMIN 500MG) in the same strength and provide identical therapeutic efficacy, meeting strict quality and safety standards.

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Diabetes Care

SITAXPERT TRIO 10/100/500

Composition:DAPAGLIFLOZIN 10MGSITAGLIPTIN 100MGMETFORMIN 500MG10'S

₹100₹328.12Saving: ₹228.12

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Substitutes of SITAXPERT TRIO 10/100/500

63% OFF

JANUPTIN TRIO PLUS

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin 500mg

₹105.00₹279.00

58% OFF

DAPKAS SGM 10/100/500MG

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin 500mg

₹121.00₹205.31

39% OFF

SITAPTIN TRIO

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin 500mg

₹175.00₹178.00

34% OFF

JOLYMET DM 10/100/500MG

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin 500mg

₹188.00₹248.43

1% OFF

SITAWICK MET TRIO 500

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin 500mg

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin 500mg

₹284.00₹380.00

SITAXPERT TRIO 10/100/500 tablet is a prescription anti-diabetic medicine used to improve blood sugar control in adults with type 2 diabetes mellitus when diet, exercise, and earlier treatment are not enough. It combines Dapagliflozin, an SGLT2 inhibitor, Sitagliptin, a DPP-4 inhibitor, and Metformin, a biguanide, to target blood sugar in different ways. This triple-combination medicine may help lower HbA1c while supporting weight goals and treatment convenience. Common strengths vary by brand and may include dapagliflozin 5 or 10 mg, sitagliptin 50 or 100 mg, with metformin 500 mg, 850 mg, or 1000 mg in immediate- or extended-release forms.

Pharmacist Note

Take SITAXPERT TRIO 10/100/500 exactly as prescribed, usually with food to reduce stomach upset from metformin. Drink enough water, especially in hot weather, because dapagliflozin can increase urination and raise the risk of dehydration. Do not stop the medicine suddenly without medical advice. During fever, vomiting, poor oral intake, major surgery, or dehydration, ask your doctor whether this medicine should be temporarily paused. Monitor blood sugar regularly, and watch for symptoms such as unusual thirst, genital itching, burning urination, severe weakness, or signs of low sugar if used with insulin or sulfonylureas.

Helps Lower High Blood Sugar

Dapagliflozin + Sitagliptin + Metformin works through three different mechanisms, which can improve day-to-day glucose control and reduce HbA1c in type 2 diabetes.

Supports Combination Treatment in Type 2 Diabetes

This fixed-dose combination may be used when a single medicine or dual therapy is not enough, improving convenience by reducing pill burden.

May Help with Weight Neutrality Or Modest Weight Benefit

Metformin is generally weight-neutral, and dapagliflozin may support modest weight reduction in some patients.

Useful in Patients Needing Step-up Oral Therapy

Current diabetes guidance supports adding medicines with complementary actions based on glucose control needs and individual risk factors.

While generally safe and well-tolerated, high doses or sensitivity can cause some side effects.

Type

Symptoms

Severity

Diabetic care

Nausea, loose stools, stomach upset, metallic taste, reduced... show more

Common

Diabetic care

Increased urination, thirst, genital fungal infection, mild ... show more

Common

Diabetic care

Headache, stuffy nose, mild dizziness

Less common

Diabetic care

Low blood sugar when combined with insulin or sulfonylureas

Serious

Diabetic care

Diabetic ketoacidosis, severe dehydration, lactic acidosis, ... show more

Serious

Dosage

The recommended SITAXPERT TRIO 10/100/500 dosage depends on your current treatme... show more

Timing

Take it once daily at the same time each day. If the product contains metformin ... show more

Limit

Do not exceed the prescribed dose. Do not double the next dose if you miss one. ... show more

Consistency

Take SITAXPERT TRIO 10/100/500 regularly at the same time every day along with d... show more

Dapagliflozin + Sitagliptin + Metformin lowers blood sugar in three complementary ways. Dapagliflozin helps the kidneys remove extra glucose through urine. Sitagliptin increases incretin activity, which helps the body release insulin when blood sugar is high and lowers glucagon. Metformin reduces glucose production in the liver and improves the body’s response to insulin. Together, they help control blood sugar more effectively in type 2 diabetes.

Pregnancy

This combination should be used in pregnancy only if your doctor clearly recommends it. Dapagliflozin is generally not recommended during pregnancy, so treatment review is important before conception or as soon as pregnancy is confirmed.

Alcohol

Alcohol can worsen dehydration and may increase the risk of low blood sugar or metformin-related lactic acidosis, especially with binge drinking or poor food intake. Limit or avoid alcohol unless your doctor says it is safe.

Driving

SITAXPERT TRIO 10/100/500 itself does not usually impair driving, but low blood sugar can affect concentration if it is taken with insulin or sulfonylureas. Do not drive if you feel shaky, sweaty, confused, or unwell.

Kidney

Kidney function should be checked before and during treatment. Dapagliflozin and metformin both need caution in kidney impairment, and dose adjustment or avoidance may be necessary in reduced renal function.

Elderly

Older adults may be more prone to dehydration, kidney problems, and dose-related side effects. Extra monitoring is often needed.

Children

This triple-combination product is generally not a routine first choice for children unless specifically prescribed by a specialist. Safety and dosing depend on the exact product and age group

Insulin

Can increase the risk of hypoglycaemia; dose adjustment may be needed

Moderate to Major

Sulfonylureas (e.g., glimepiride)

Higher chance of low blood sugar when combined

Moderate to Major

Diuretics (e.g., furosemide)

May increase dehydration, dizziness, and low blood pressure

Moderate

ACE inhibitors / antihypertensives

May add to blood-pressure-lowering and dizziness in some patients

Moderate

Alcohol

Can raise the risk of lactic acidosis or hypoglycaemia in susceptible patients

Major

American Diabetes Association – Standards of Care in Diabetes
https://professional.diabetes.org/standards-of-care
ADA – Pharmacologic Approaches to Glycemic Treatment
https://diabetesjournals.org/care/article/48/Supplement_1/S181/157569/9-Pharmacologic-Approaches-to-Glycemic-Treatment
NICE Guideline NG28 – Type 2 diabetes in adults: management
https://www.nice.org.uk/guidance/ng28
NHS – Dapagliflozin
https://www.nhs.uk/medicines/dapagliflozin/
MedlinePlus – Sitagliptin Drug Information
https://medlineplus.gov/druginfo/meds/a606023.html
MedlinePlus – Metformin Drug Information
https://medlineplus.gov/druginfo/meds/a696005.html

Disclaimer

: The information provided on this page is for informational and educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.

WRITTEN BY

Dr. Helan, PharmD

REVIEWED BY

Dr. Lakshmi MBBS, MD

LAST UPDATED

Oct 12, 2024